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  مقایسه اثر دولوکستین با گاباپنتین در درمان نوروپاتی محیطی ناشی از دیابت
  درمان چنددارویی برای بعضی از بیماران
  دوقطبی لازم است و به‌ خوبی در نوجوانان تحمل می‌شود .
  میلی‌اکی‌والان بر لیتر وگاباپانتین تا
  400 میلی‌گرم افزایش یافت. پرسش‌نامه‌های مقیاس درجه‌بندی مانیای یانگ ، افسردگی بک واضطراب هامیلتون هر
  2 هفته یک بار تکمیل شده است. عوارض دارویی هر 2 هفته یک بار، سطح سرمی لیتیوم هفتگی و وزن بیماران در ابتدا وانتهای پژوهش بررسی گردید.
  کارآزمایی‌های تصادفی‌سازی شده، دوسو-کور را با طول مدت
  دو هفته یا بیشتر وارد کردیم، که به مقایسه گاباپنتین (با هر روش تجویزی) با دارونما یا درمان فعال دیگری برای مدیریت درد نوروپاتیک، با ارزیابی درد گزارش شده
  توسط شرکت‌کننده، پرداختند.
  داروی گاباپنتین معمولا برای درمان درد نوروپاتیک (درد ناشی از آسیب
  به عصب) تجویز می‌شود.
  همچنین نشان داده شده­ است که این دارو اثرات مفیدی روی درد­های نوروپاتیک، نوروپاتی دیابتی و نورالژی پست
  هرپتیک دارد (3، 4، 5 و 6). بعدها از این دارو
  به صورت تک درمانی در درمان صرع (7 و 8) و همینطور جهت تسکین بسیاری از دردهای عصبی (9 و 10) و میگرن نیز استفاده گردید.
  
  عدم متابولیزه شدن این دارو در بدن، دفع کلیوی سریع، فقدان تداخلات دارویی و
  تحمل­پذیری خوب آن، باعث کاربرد وسیع­تر گاباپنتین گردید (12 و 13).

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